Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting

Repeated exposure to pathogens or their antigens triggers anamnestic antibody responses that are higher in magnitude and affinity than the primary response. These involve reengagement of memory B cell (MBC) clones, the diversity and specificity of which determine the breadth and effectiveness of the...

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Vydáno v:Cell
Hlavní autoři: Mesin, Luka, Schiepers, Ariën, Ersching, Jonatan, Barbulescu, Alexandru, Cavazzoni, Cecília B., Angelini, Alessandro, Okada, Takaharu, Kurosaki, Tomohiro, Victora, Gabriel D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6958527/
https://ncbi.nlm.nih.gov/pubmed/31866068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.11.032
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