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Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone

Multiple myeloma is characterized by accumulation of malignant plasma cells in the bone marrow. Most patients suffer from an osteolytic bone disease, caused by increased bone degradation and reduced bone formation. Bone morphogenetic protein 4 (BMP4) is important for both pre‐ and postnatal bone for...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:JBMR Plus
Päätekijät: Westhrin, Marita, Holien, Toril, Zahoor, Muhammad, Moen, Siv Helen, Buene, Glenn, Størdal, Berit, Hella, Hanne, Yuan, Huipin, de Bruijn, Joost D, Martens, Anton, Groen, Richard WJ, Bosch, Fatima, Smith, Ulf, Sponaas, Anne‐Marit, Sundan, Anders, Standal, Therese
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957984/
https://ncbi.nlm.nih.gov/pubmed/31956851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10247
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