Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone

Multiple myeloma is characterized by accumulation of malignant plasma cells in the bone marrow. Most patients suffer from an osteolytic bone disease, caused by increased bone degradation and reduced bone formation. Bone morphogenetic protein 4 (BMP4) is important for both pre‐ and postnatal bone for...

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Bibliografski detalji
Izdano u:JBMR Plus
Glavni autori: Westhrin, Marita, Holien, Toril, Zahoor, Muhammad, Moen, Siv Helen, Buene, Glenn, Størdal, Berit, Hella, Hanne, Yuan, Huipin, de Bruijn, Joost D, Martens, Anton, Groen, Richard WJ, Bosch, Fatima, Smith, Ulf, Sponaas, Anne‐Marit, Sundan, Anders, Standal, Therese
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957984/
https://ncbi.nlm.nih.gov/pubmed/31956851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10247
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