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Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone

Multiple myeloma is characterized by accumulation of malignant plasma cells in the bone marrow. Most patients suffer from an osteolytic bone disease, caused by increased bone degradation and reduced bone formation. Bone morphogenetic protein 4 (BMP4) is important for both pre‐ and postnatal bone for...

詳細記述

保存先:
書誌詳細
出版年:JBMR Plus
主要な著者: Westhrin, Marita, Holien, Toril, Zahoor, Muhammad, Moen, Siv Helen, Buene, Glenn, Størdal, Berit, Hella, Hanne, Yuan, Huipin, de Bruijn, Joost D, Martens, Anton, Groen, Richard WJ, Bosch, Fatima, Smith, Ulf, Sponaas, Anne‐Marit, Sundan, Anders, Standal, Therese
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957984/
https://ncbi.nlm.nih.gov/pubmed/31956851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10247
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