Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation

Lysosomes are membrane-surrounded cytoplasmic organelles filled with a powerful cocktail of hydrolases. Besides degrading cellular constituents inside the lysosomal lumen, lysosomal hydrolases promote tissue remodeling when delivered to the extracellular space and cell death when released to the cyt...

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Foilsithe in:Nat Commun
Main Authors: Hämälistö, Saara, Stahl, Jonathan Lucien, Favaro, Elena, Yang, Qing, Liu, Bin, Christoffersen, Line, Loos, Ben, Guasch Boldú, Claudia, Joyce, Johanna A., Reinheckel, Thomas, Barisic, Marin, Jäättelä, Marja
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957743/
https://ncbi.nlm.nih.gov/pubmed/31932607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14009-0
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