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Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation

Lysosomes are membrane-surrounded cytoplasmic organelles filled with a powerful cocktail of hydrolases. Besides degrading cellular constituents inside the lysosomal lumen, lysosomal hydrolases promote tissue remodeling when delivered to the extracellular space and cell death when released to the cyt...

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Publicado en:Nat Commun
Autores principales: Hämälistö, Saara, Stahl, Jonathan Lucien, Favaro, Elena, Yang, Qing, Liu, Bin, Christoffersen, Line, Loos, Ben, Guasch Boldú, Claudia, Joyce, Johanna A., Reinheckel, Thomas, Barisic, Marin, Jäättelä, Marja
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957743/
https://ncbi.nlm.nih.gov/pubmed/31932607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14009-0
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