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Methods for the functional quantification of lysosomal membrane permeabilization: a hallmark of lysosomal cell death

Lysosomal cell death is triggered by lysosomal membrane permeabilization (LMP) and subsequent release of lysosomal hydrolases from the lysosomal lumen into the cytosol. Once released to the cytosol, the lysosomal cathepsin proteases act as executioner proteases for the subsequent cell death - either...

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Dettagli Bibliografici
Pubblicato in:Methods Cell Biol
Autori principali: Aits, Sonja, Jäättelä, Marja, Nylandsted, Jesper
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611294/
https://ncbi.nlm.nih.gov/pubmed/25665450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mcb.2014.10.032
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