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Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion
A number of diseases are due to lysosomal destabilization, which results in damaging cell loss. To investigate the mechanisms of lysosomal cell death, we characterized the cytotoxic action of two widely used quinolone antibiotics: ciprofloxacin (CPX) or norfloxacin (NFX). CPX or NFX plus UV light (N...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193790/ https://ncbi.nlm.nih.gov/pubmed/12756268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021952 |
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