Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes

Muscle contraction may protect against the effects of chemotherapy to cause skeletal muscle atrophy, but the mechanisms underlying these benefits are unclear. To address this question, we utilized in vitro modeling of contraction and mechanotransduction in C2C12 myotubes treated with doxorubicin (DO...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Cell Physiol
Asıl Yazarlar: Guigni, Blas A., Fix, Dennis K., Bivona, Joseph J., Palmer, Bradley M., Carson, James A., Toth, Michael J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957384/
https://ncbi.nlm.nih.gov/pubmed/31532714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00148.2019
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