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Inhibition of mitochondrial and cytosolic calpain attenuates atrophy in myotubes co-cultured with colon carcinoma cells

Cancer cachexia is a life-threatening syndrome characterized by muscle atrophy. Cancer cachectic muscle atrophy (CCMA) is associated with mitochondrial injury. Mitochondrial calpains have been reported to induce mitochondrial injury in mouse cardiomyocytes and pulmonary smooth muscle. In the present...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Zeng, Xianliang, Zhao, Li, Chen, Sizeng, Li, Xiantao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7798110/
https://ncbi.nlm.nih.gov/pubmed/33552245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12385
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