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Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells

Cancer cachexia is a result of increased protein degradation and decreased protein synthesis. The multifunctional circulating hormone ghrelin promotes synthesis and inhibits degradation of muscle protein, but its mechanism of action is not fully understood. Here, we investigated whether co-culturing...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zeng, Xianliang, Chen, Sizeng, Yang, Yang, Ke, Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641175/
https://ncbi.nlm.nih.gov/pubmed/29069832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20531
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