Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice

Cachexia is a wasting syndrome associated with cancer, AIDS, multiple sclerosis, and several other disease states. It is characterized by weight loss, fatigue, loss of appetite, and skeletal muscle atrophy and is associated with poor patient prognosis, making it an important treatment target. Ghreli...

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Detalhes bibliográficos
Main Authors: Porporato, Paolo E., Filigheddu, Nicoletta, Reano, Simone, Ferrara, Michele, Angelino, Elia, Gnocchi, Viola F., Prodam, Flavia, Ronchi, Giulia, Fagoonee, Sharmila, Fornaro, Michele, Chianale, Federica, Baldanzi, Gianluca, Surico, Nicola, Sinigaglia, Fabiola, Perroteau, Isabelle, Smith, Roy G., Sun, Yuxiang, Geuna, Stefano, Graziani, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561827/
https://ncbi.nlm.nih.gov/pubmed/23281394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39920
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