Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice

Sarcopenia, the decline in muscle mass and functionality during aging, might arise from age-associated endocrine dysfunction. Ghrelin is a hormone circulating in both acylated (AG) and unacylated (UnAG) forms with anti-atrophic activity on skeletal muscle. Here, we show that not only lifelong overex...

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Publicat a:Aging (Albany NY)
Autors principals: Agosti, Emanuela, De Feudis, Marilisa, Angelino, Elia, Belli, Roberta, Alves Teixeira, Maraiza, Zaggia, Ivan, Tamiso, Edoardo, Raiteri, Tommaso, Scircoli, Andrea, Ronzoni, Flavio L., Muscaritoli, Maurizio, Graziani, Andrea, Prodam, Flavia, Sampaolesi, Maurilio, Costelli, Paola, Ferraro, Elisabetta, Reano, Simone, Filigheddu, Nicoletta
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425472/
https://ncbi.nlm.nih.gov/pubmed/32712599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103802
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