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Acylated and unacylated ghrelin inhibit atrophy in myotubes co-cultured with colon carcinoma cells

Cancer cachexia is a result of increased protein degradation and decreased protein synthesis. The multifunctional circulating hormone ghrelin promotes synthesis and inhibits degradation of muscle protein, but its mechanism of action is not fully understood. Here, we investigated whether co-culturing...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zeng, Xianliang, Chen, Sizeng, Yang, Yang, Ke, Zhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641175/
https://ncbi.nlm.nih.gov/pubmed/29069832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20531
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