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Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes

Muscle contraction may protect against the effects of chemotherapy to cause skeletal muscle atrophy, but the mechanisms underlying these benefits are unclear. To address this question, we utilized in vitro modeling of contraction and mechanotransduction in C2C12 myotubes treated with doxorubicin (DO...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Guigni, Blas A., Fix, Dennis K., Bivona, Joseph J., Palmer, Bradley M., Carson, James A., Toth, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957384/
https://ncbi.nlm.nih.gov/pubmed/31532714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00148.2019
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