A role for phagocytosis in inducing cell death during thymocyte negative selection

Autoreactive thymocytes are eliminated during negative selection in the thymus, a process important for establishing self-tolerance. Thymic phagocytes serve to remove dead thymocytes, but whether they play additional roles during negative selection remains unclear. Here, using a murine thymic slice...

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Udgivet i:eLife
Main Authors: Kurd, Nadia S, Lutes, Lydia K, Yoon, Jaewon, Chan, Shiao Wei, Dzhagalov, Ivan L, Hoover, Ashley R, Robey, Ellen A
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957271/
https://ncbi.nlm.nih.gov/pubmed/31868579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48097
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