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Stable interactions and sustained T cell receptor signaling characterize thymocyte-thymocyte interactions that support negative selection(a)
Negative selection is one of the primary mechanisms that render T cells tolerant to self. Thymic dendritic cells play an important role in negative selection, in line with their ability to induce migratory arrest and sustained T cell receptor (TCR) signals. Thymocytes themselves display self-peptide...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297692/ https://ncbi.nlm.nih.gov/pubmed/25520400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400169 |
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