Urocortin 2 Gene Transfer Improves Heart Function in Aged Mice

Prevalence of left ventricular (LV) systolic and diastolic dysfunction increases with aging. We previously reported that urocortin 2 (Ucn2) gene transfer increases heart function in mice with heart failure with reduced ejection fraction. Here, we test the hypotheses that (1) Ucn2 gene transfer will...

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Publicado en:Mol Ther
Autores principales: Giamouridis, Dimosthenis, Gao, Mei Hua, Lai, N. Chin, Guo, Tracy, Miyanohara, Atsushi, Blankesteijn, W. Matthijs, Biessen, Erik A.L., Hammond, H. Kirk
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953892/
https://ncbi.nlm.nih.gov/pubmed/31676153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.10.003
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