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Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal

UCn2 and UCn3 peptides have recently been infused to treat patients with heart failure (HF) but are limited by their short half-lives. A 1-time intravenous injection of virus vectors encoding UCn2 or UCn3 provided sustained increases in plasma concentrations of the peptides. This was associated with...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Giamouridis, Dimosthenis, Gao, Mei Hua, Lai, N. Chin, Tan, Zhen, Kim, Young Chul, Guo, Tracy, Miyanohara, Atsushi, Blankesteijn, W. Matthijs, Biessen, Erik, Hammond, H. Kirk
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059348/
https://ncbi.nlm.nih.gov/pubmed/30062211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.12.004
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