Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal

UCn2 and UCn3 peptides have recently been infused to treat patients with heart failure (HF) but are limited by their short half-lives. A 1-time intravenous injection of virus vectors encoding UCn2 or UCn3 provided sustained increases in plasma concentrations of the peptides. This was associated with...

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Bibliografiske detaljer
Udgivet i:JACC Basic Transl Sci
Main Authors: Giamouridis, Dimosthenis, Gao, Mei Hua, Lai, N. Chin, Tan, Zhen, Kim, Young Chul, Guo, Tracy, Miyanohara, Atsushi, Blankesteijn, W. Matthijs, Biessen, Erik, Hammond, H. Kirk
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
PRECLINICAL RESEARCH
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059348/
https://ncbi.nlm.nih.gov/pubmed/30062211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.12.004
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