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Nascent polypeptide domain topology and elongation rate direct the cotranslational hierarchy of Hsp70 and TRiC/CCT
Cotranslational protein folding requires assistance from elaborate ribosome-associated chaperone networks. It remains unclear how the changing information in a growing nascent polypeptide dictates the recruitment of functionally distinct chaperones. Here, we used ribosome profiling to define the pri...
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Foilsithe in: | Mol Cell |
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Main Authors: | , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
2019
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6953483/ https://ncbi.nlm.nih.gov/pubmed/31400849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.036 |
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