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Probing thermostability of detergent-solubilized CB(2) receptor by parallel G protein–activation and ligand-binding assays
G protein–coupled receptors (GPCRs) comprise a large class of integral membrane proteins involved in the regulation of a broad spectrum of physiological processes and are a major target for pharmaceutical drug development. Structural studies can help advance the rational design of novel specific pha...
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| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952600/ https://ncbi.nlm.nih.gov/pubmed/31776188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010696 |
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