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Tailoring early-phase clinical trial design to address multiple research objectives

INTRODUCTION: In contemporary oncology drug development, implementation of novel early-phase designs with the ability to address multiple research objectives is needed to better refine regimens. This paper describes an adaptive design strategy for identifying a range of optimal regimens based on two...

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Bibliografiska uppgifter
I publikationen:Cancer Immunol Immunother
Huvudupphovsmän: Wages, Nolan A., Slingluff, Craig L., Bullock, Timothy N., Petroni, Gina R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952569/
https://ncbi.nlm.nih.gov/pubmed/31807879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02442-5
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