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A web tool for designing and conducting phase I trials using the continual reassessment method

BACKGROUND: Broad implementation of model-based dose-finding methods, such as the continual reassessment method (CRM), has been limited, with traditional or modified 3 + 3 designs remaining in frequent use. Part of the reason is the lack of reliable, easy-to-use, and robust software tools for design...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Wages, Nolan A., Petroni, Gina R.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799912/
https://ncbi.nlm.nih.gov/pubmed/29402249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4038-x
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