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A web tool for designing and conducting phase I trials using the continual reassessment method
BACKGROUND: Broad implementation of model-based dose-finding methods, such as the continual reassessment method (CRM), has been limited, with traditional or modified 3 + 3 designs remaining in frequent use. Part of the reason is the lack of reliable, easy-to-use, and robust software tools for design...
Enregistré dans:
| Publié dans: | BMC Cancer |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5799912/ https://ncbi.nlm.nih.gov/pubmed/29402249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4038-x |
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