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A web tool for designing and conducting phase I trials using the continual reassessment method

BACKGROUND: Broad implementation of model-based dose-finding methods, such as the continual reassessment method (CRM), has been limited, with traditional or modified 3 + 3 designs remaining in frequent use. Part of the reason is the lack of reliable, easy-to-use, and robust software tools for design...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Wages, Nolan A., Petroni, Gina R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799912/
https://ncbi.nlm.nih.gov/pubmed/29402249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4038-x
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