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Arc silence aggravates traumatic neuronal injury via mGluR1-mediated ER stress and necroptosis

Delayed neuronal death is associated with neurological deficits and mortality after traumatic brain injury (TBI), where post-synaptic density (PSD) proteins are thought to play key roles. The immediate-early gene (IEG) coded protein Arc is a brain-specific PSD protein that controls synaptic plastici...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Chen, Tao, Zhu, Jie, Wang, Yu-Hai, Hang, Chun-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952410/
https://ncbi.nlm.nih.gov/pubmed/31919348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2198-5
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