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Chimeric Capsid Proteins Impact Transduction Efficiency of Haploid Adeno-Associated Virus Vectors

Our previous studies have demonstrated that haploid AAV vectors made from capsids of two different serotypes induced high transduction and prevented serotype-specific antibody binding. In this study, we explored the transduction efficiency of several haploid viruses, which were made from the VP1/VP2...

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Détails bibliographiques
Publié dans:Viruses
Auteurs principaux: Chai, Zheng, Zhang, Xintao, Dobbins, Amanda Lee, Frost, Ellie Azure, Samulski, R. Jude, Li, Chengwen
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950324/
https://ncbi.nlm.nih.gov/pubmed/31835440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11121138
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