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Development of an Imine Chaperone for Selective C-H Functionalization of Alcohols via Radical Relay

The design of a radical relay chaperone to promote selective C-H functionalizations is described. A saccharine-based imine was found to be uniquely suited to effect C-H amination of alcohols via an in situ generated hemiaminal. This radical chaperone facilitates the mild generation of an N-centered...

詳細記述

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書誌詳細
出版年:J Org Chem
主要な著者: Nakafuku, Kohki M., Twumasi, Raymond K., Vanitcha, Avassaya, Wappes, Ethan A., Namitharan, Kayambu, Bekkaye, Mathieu, Nagib, David A.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948922/
https://ncbi.nlm.nih.gov/pubmed/31513401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02052
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