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Enantioselective radical C–H amination for the synthesis of β-amino alcohols

Asymmetric, radical C–H functionalizations are rare, yet powerful tools for solving modern synthetic challenges. Specifically, the enantio- and regio-selective C–H amination of alcohols to access medicinally valuable, chiral β-amino alcohols remains elusive. To solve this challenge, a radical relay...

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Detalles Bibliográficos
Publicado en:Nat Chem
Main Authors: Nakafuku, Kohki M., Zhang, Zuxiao, Wappes, Ethan A., Stateman, Leah M., Chen, Andrew D., Nagib, David A.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390680/
https://ncbi.nlm.nih.gov/pubmed/32572164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-020-0482-8
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