Role of HLA-B Exon 1 in Graft-versus-Host Disease After Unrelated Donor Transplantation: A Retrospective Cohort Study

BACKGROUND: The success of unrelated hematopoietic-cell transplantation (HCT) is limited by graft-versus-host disease (GVHD). A sequence dimorphism in exon one of HLA-B gives rise to leader peptides containing methionine (M) or threonine (T) which differentially influence NK and T-cell alloresponses...

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Publicado en:Lancet Haematol
Autores principales: Petersdorf, Effie W., Carrington, Mary, O’hUigin, Colm, Bengtsson, Mats, De Santis, Dianne, Dubois, Valerie, Gooley, Ted, Horowitz, Mary, Hsu, Katharine, Madrigal, J. Alejandro, Maiers, Martin J., Malkki, Mari, McKallor, Caroline, Morishima, Yasuo, Oudshoorn, Machteld, Spellman, Stephen R., Villard, Jean, Stevenson, Phil
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948919/
https://ncbi.nlm.nih.gov/pubmed/31669248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(19)30208-X
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