Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice

Mammalian focal adhesion proteins Pinch1 and Pinch2 regulate integrin activation and cell–extracellular matrix adhesion and migration. Here, we show that deleting Pinch1 in osteocytes and mature osteoblasts using the 10-kb mouse Dmp1-Cre and Pinch2 globally (double KO; dKO) results in severe osteope...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wang, Yishu, Yan, Qinnan, Zhao, Yiran, Liu, Xin, Lin, Simin, Zhang, Peijun, Ma, Liting, Lai, Yumei, Bai, Xiaochun, Liu, Chuanju, Wu, Chuanyue, Feng, Jian Q., Chen, Di, Cao, Huiling, Xiao, Guozhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948870/
https://ncbi.nlm.nih.gov/pubmed/31723057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131692
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados