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Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice
Mammalian focal adhesion proteins Pinch1 and Pinch2 regulate integrin activation and cell–extracellular matrix adhesion and migration. Here, we show that deleting Pinch1 in osteocytes and mature osteoblasts using the 10-kb mouse Dmp1-Cre and Pinch2 globally (double KO; dKO) results in severe osteope...
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| Yayımlandı: | JCI Insight |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6948870/ https://ncbi.nlm.nih.gov/pubmed/31723057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131692 |
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