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Hemagglutinin head-specific responses dominate over stem-specific responses following prime boost with mismatched vaccines

Broadly neutralizing Abs targeting the HA stem can provide broad protection against different influenza subtypes, raising the question of how best to elicit such Abs. We have previously demonstrated that vaccination with pandemic live-attenuated influenza vaccine (pLAIV) establishes immune memory fo...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Jegaskanda, Sinthujan, Andrews, Sarah F., Wheatley, Adam K., Yewdell, Jonathan W., McDermott, Adrian B., Subbarao, Kanta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948858/
https://ncbi.nlm.nih.gov/pubmed/31723058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129035
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