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Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals

Recently, several neutralizing anti-HIV antibodies have been isolated from memory B cells of HIV-infected individuals. Despite extensive evidence of B cell dysfunction in HIV disease, little is known about the cells from which these rare HIV-specific antibodies originate. Accordingly, we used HIV en...

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Detalhes bibliográficos
Main Authors: Kardava, Lela, Moir, Susan, Shah, Naisha, Wang, Wei, Wilson, Richard, Buckner, Clarisa M., Santich, Brian H., Kim, Leo J.Y., Spurlin, Emily E., Nelson, Amy K., Wheatley, Adam K., Harvey, Christopher J., McDermott, Adrian B., Wucherpfennig, Kai W., Chun, Tae-Wook, Tsang, John S., Li, Yuxing, Fauci, Anthony S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071400/
https://ncbi.nlm.nih.gov/pubmed/24892810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74351
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