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Bone marrow plasma cells are a primary source of serum HIV-1-specific antibodies in chronically infected individuals

Several potent and broadly neutralizing antibodies to HIV-1 have been isolated recently from peripheral blood B cells of infected individuals, based on pre-screening of antibody activity in the serum. However, little is known regarding the cells that make the antibodies that circulate in the blood....

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Foilsithe in:J Immunol
Main Authors: Montezuma-Rusca, Jairo Mauricio, Moir, Susan, Kardava, Lela, Buckner, Clarisa M., Louie, Aaron, Kim, Leo J.Y., Santich, Brian H., Wang, Wei, Fankuchen, Olivia R., Diaz, Gabriella, Daub, Janine R., Rosenzweig, Sergio D., Chun, Tae-Wook, Li, Yuxing, Braylan, Raul Cipriano, Calvo, Katherine R., Fauci, Anthony S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355319/
https://ncbi.nlm.nih.gov/pubmed/25681347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402424
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