Characterization of Plasmablasts in the Blood of HIV-Infected Viremic Individuals: Evidence for Nonspecific Immune Activation

Terminal differentiation of B cells and hypergammaglobulinemia are hallmarks of B-cell hyperactivity in HIV disease. Plasmablasts are terminally differentiating B cells that circulate transiently in the blood following infection or vaccination; however, in HIV infection, they arise early and are mai...

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Autori principali: Buckner, Clarisa M., Moir, Susan, Ho, Jason, Wang, Wei, Posada, Jacqueline G., Kardava, Lela, Funk, Emily K., Nelson, Amy K., Li, Yuxing, Chun, Tae-Wook, Fauci, Anthony S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648153/
https://ncbi.nlm.nih.gov/pubmed/23487459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00094-13
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