Single-Dose, Preoperative Vitamin-D Supplementation Decreases Infection in a Mouse Model of Periprosthetic Joint Infection

BACKGROUND: Despite recent advances, infection remains the most common etiology of arthroplasty failure. Recent work suggests that 25-hydroxyvitamin D (25D) deficiency correlates with the frequency of periprosthetic joint infection (PJI). We endeavored to examine whether 25D(3) deficiency leads to i...

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Udgivet i:J Bone Joint Surg Am
Main Authors: Hegde, Vishal, Dworsky, Erik M., Stavrakis, Alexandra I., Loftin, Amanda H., Zoller, Stephen D., Park, Howard Y., Richman, Sherif, Johansen, Daniel, Hu, Yan, Taylor, Julie A., Hamad, Christopher D., Chun, Rene F., Xi, Weixian, Adams, John S., Bernthal, Nicholas M.
Format: Artigo
Sprog:Inglês
Udgivet: The Journal of Bone and Joint Surgery, Inc. 2017
Fag:
Scientific Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948832/
https://ncbi.nlm.nih.gov/pubmed/29040128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.16.01598
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