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Single-Dose, Preoperative Vitamin-D Supplementation Decreases Infection in a Mouse Model of Periprosthetic Joint Infection

BACKGROUND: Despite recent advances, infection remains the most common etiology of arthroplasty failure. Recent work suggests that 25-hydroxyvitamin D (25D) deficiency correlates with the frequency of periprosthetic joint infection (PJI). We endeavored to examine whether 25D(3) deficiency leads to i...

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Publicado en:J Bone Joint Surg Am
Main Authors: Hegde, Vishal, Dworsky, Erik M., Stavrakis, Alexandra I., Loftin, Amanda H., Zoller, Stephen D., Park, Howard Y., Richman, Sherif, Johansen, Daniel, Hu, Yan, Taylor, Julie A., Hamad, Christopher D., Chun, Rene F., Xi, Weixian, Adams, John S., Bernthal, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado: The Journal of Bone and Joint Surgery, Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948832/
https://ncbi.nlm.nih.gov/pubmed/29040128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.16.01598
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