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Single-Dose, Preoperative Vitamin-D Supplementation Decreases Infection in a Mouse Model of Periprosthetic Joint Infection

BACKGROUND: Despite recent advances, infection remains the most common etiology of arthroplasty failure. Recent work suggests that 25-hydroxyvitamin D (25D) deficiency correlates with the frequency of periprosthetic joint infection (PJI). We endeavored to examine whether 25D(3) deficiency leads to i...

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Détails bibliographiques
Publié dans:J Bone Joint Surg Am
Auteurs principaux: Hegde, Vishal, Dworsky, Erik M., Stavrakis, Alexandra I., Loftin, Amanda H., Zoller, Stephen D., Park, Howard Y., Richman, Sherif, Johansen, Daniel, Hu, Yan, Taylor, Julie A., Hamad, Christopher D., Chun, Rene F., Xi, Weixian, Adams, John S., Bernthal, Nicholas M.
Format: Artigo
Langue:Inglês
Publié: The Journal of Bone and Joint Surgery, Inc. 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948832/
https://ncbi.nlm.nih.gov/pubmed/29040128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.16.01598
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