MiR-16 regulates crosstalk in NF-κB tolerogenic inflammatory signaling between myeloma cells and bone marrow macrophages

High levels of circulating miR-16 in the serum of multiple myeloma (MM) patients are independently associated with longer survival. Although the tumor suppressor function of intracellular miR-16 in MM plasma cells (PCs) has been elucidated, its extracellular role in maintaining a nonsupportive cance...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Khalife, Jihane, Ghose, Jayeeta, Martella, Marianna, Viola, Domenico, Rocci, Alberto, Troadec, Estelle, Terrazas, Cesar, Satoskar, Abhay R., Gunes, Emine Gulsen, Dona, Ada, Sanchez, James F., Bergsagel, P. Leif, Chesi, Marta, Pozhitkov, Alex, Rosen, Steven, Marcucci, Guido, Keats, Jonathan J., Hofmeister, Craig C., Krishnan, Amrita, Caserta, Enrico, Pichiorri, Flavia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948777/
https://ncbi.nlm.nih.gov/pubmed/31593552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129348
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