MiR-16 regulates crosstalk in NF-κB tolerogenic inflammatory signaling between myeloma cells and bone marrow macrophages

High levels of circulating miR-16 in the serum of multiple myeloma (MM) patients are independently associated with longer survival. Although the tumor suppressor function of intracellular miR-16 in MM plasma cells (PCs) has been elucidated, its extracellular role in maintaining a nonsupportive cance...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Khalife, Jihane, Ghose, Jayeeta, Martella, Marianna, Viola, Domenico, Rocci, Alberto, Troadec, Estelle, Terrazas, Cesar, Satoskar, Abhay R., Gunes, Emine Gulsen, Dona, Ada, Sanchez, James F., Bergsagel, P. Leif, Chesi, Marta, Pozhitkov, Alex, Rosen, Steven, Marcucci, Guido, Keats, Jonathan J., Hofmeister, Craig C., Krishnan, Amrita, Caserta, Enrico, Pichiorri, Flavia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948777/
https://ncbi.nlm.nih.gov/pubmed/31593552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129348
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