Silencing of Long Non-coding RNA HOTTIP Reduces Inflammation in Rheumatoid Arthritis by Demethylation of SFRP1

Accumulating evidence suggests long non-coding RNAs (lncRNAs) play crucial roles in the pathogenesis of rheumatoid arthritis (RA). Here, we aimed to define the role of HOXA transcript at the distal tip (HOTTIP) in RA pathogenesis in relation to SFRP1 methylation and Wnt signaling pathway. HOTTIP was...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Nucleic Acids
Egile Nagusiak: Hu, Xumin, Tang, Jianhua, Hu, Xuyun, Bao, Peng, Deng, Weixi, Wu, Jionglin, Liang, Yuwei, Chen, Zhipeng, Gao, Liangbin, Tang, Yong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948255/
https://ncbi.nlm.nih.gov/pubmed/31902746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.11.015
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