Rheumatoid Arthritis Fibroblast-like Synoviocyte Suppression Mediated by PTEN Involves Survivin Gene Silencing

Survivin is a proto-oncogene biomarker known for its anti-apoptotic and cell cycle regulating properties induced by the activation of the phosphoinositide 3-kinase (PI3K)/Akt pathway. In the context of non-cancer pathology, such as rheumatoid arthritis (RA), survivin has emerged as a feature associa...

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Udgivet i:Sci Rep
Main Authors: Chen, Danna, Liu, Dongdong, Liu, Dan, He, Min, Peng, Anping, Xu, Jiarui, Lin, Li, Luo, Fudong, Chen, Lin, Huang, Xianzhang, Zhuang, Junhua, Xu, Jianhua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428713/
https://ncbi.nlm.nih.gov/pubmed/28337018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00517-w
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