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PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is characterized by a tumor-like expansion of the synovium and subsequent destruction of adjacent articular cartilage and bone. In our previous work we showed that phosphatase and tension homolog deleted on chromosome 10 (PTEN) contributes to the activation of fibroblast-li...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Li, Xiao-Feng, Wu, Sha, Yan, Qi, Wu, Yuan-Yuan, Chen, He, Yin, Su-Qin, Chen, Xin, Wang, Hua, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296842/
https://ncbi.nlm.nih.gov/pubmed/34305608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.700373
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