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PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is characterized by a tumor-like expansion of the synovium and subsequent destruction of adjacent articular cartilage and bone. In our previous work we showed that phosphatase and tension homolog deleted on chromosome 10 (PTEN) contributes to the activation of fibroblast-li...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Xiao-Feng, Wu, Sha, Yan, Qi, Wu, Yuan-Yuan, Chen, He, Yin, Su-Qin, Chen, Xin, Wang, Hua, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296842/
https://ncbi.nlm.nih.gov/pubmed/34305608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.700373
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