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Enhancement of lung levels of antibiotics by Ambroxol and Bromhexine

INTRODUCTION: Major unmet needs remain for improved antibiotic treatment in lung infections. While development of new antibiotics is needed to overcome resistance, other approaches to optimize therapy using existing agents are also attractive. Ambroxol induces lung autophagy at human-relevant doses...

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Pubblicato in:Expert Opin Drug Metab Toxicol
Autori principali: Deretic, Vojo, Timmins, Graham S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947664/
https://ncbi.nlm.nih.gov/pubmed/30721101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2019.1578748
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