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Enhancement of lung levels of antibiotics by Ambroxol and Bromhexine

INTRODUCTION: Major unmet needs remain for improved antibiotic treatment in lung infections. While development of new antibiotics is needed to overcome resistance, other approaches to optimize therapy using existing agents are also attractive. Ambroxol induces lung autophagy at human-relevant doses...

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Bibliografische gegevens
Gepubliceerd in:Expert Opin Drug Metab Toxicol
Hoofdauteurs: Deretic, Vojo, Timmins, Graham S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947664/
https://ncbi.nlm.nih.gov/pubmed/30721101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2019.1578748
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