Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression and autophagy

Gartanin, a 4-prenylated xanthone, has been identified from the purple mangosteen fruit as a potent growth inhibitor of various cancer cell lines, including prostate cancer. However, much of Gartanin’s anti-cancer mechanism remains unknown. We have discovered that Gartanin docked onto the regulatory...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Pham, Victor, Rendon, Raymond, Le, Vinh X, Tippin, Matthew, Fu, Dong-Jun, Le, Thanh H, Miller, Marvin, Agredano, Ericka, Cedano, Jose, Zi, Xiaolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946862/
https://ncbi.nlm.nih.gov/pubmed/31782573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23140
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados