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Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Based on engineered or bacterial nucleases, the development of genome editing technologies has opened up the possibility of directly targeting and modifying genomic sequences in almost all eukaryotic cells. Genome editing has extended our ability to elucidate the contribution of genetics to disease...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Li, Hongyi, Yang, Yang, Hong, Weiqi, Huang, Mengyuan, Wu, Min, Zhao, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946647/
https://ncbi.nlm.nih.gov/pubmed/32296011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0089-y
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