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Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Based on engineered or bacterial nucleases, the development of genome editing technologies has opened up the possibility of directly targeting and modifying genomic sequences in almost all eukaryotic cells. Genome editing has extended our ability to elucidate the contribution of genetics to disease...

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Podrobná bibliografie
Vydáno v:Signal Transduct Target Ther
Hlavní autoři: Li, Hongyi, Yang, Yang, Hong, Weiqi, Huang, Mengyuan, Wu, Min, Zhao, Xia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946647/
https://ncbi.nlm.nih.gov/pubmed/32296011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0089-y
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