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Mycobacterium tuberculosis exploits a heterohexameric enoyl-CoA hydratase retro-aldolase complex for cholesterol catabolism
Cholesterol catabolism plays an important role in Mycobacterium tuberculosis’s (Mtb’s) survival and persistence in the host. Mtb exploits three β-oxidation cycles to fully degrade the side-chain of cholesterol. Five cistronic genes in a single operon encode three enzymes, 3-oxo-4-pregnene-20-carboxy...
Gardado en:
| Publicado en: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6946549/ https://ncbi.nlm.nih.gov/pubmed/31568719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00673 |
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