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Mycobacterium tuberculosis exploits a heterohexameric enoyl-CoA hydratase retro-aldolase complex for cholesterol catabolism

Cholesterol catabolism plays an important role in Mycobacterium tuberculosis’s (Mtb’s) survival and persistence in the host. Mtb exploits three β-oxidation cycles to fully degrade the side-chain of cholesterol. Five cistronic genes in a single operon encode three enzymes, 3-oxo-4-pregnene-20-carboxy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Yuan, Tianao, Yang, Meng, Gehring, Kalle, Sampson, Nicole S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946549/
https://ncbi.nlm.nih.gov/pubmed/31568719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00673
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