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A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis
[Image: see text] The Mycobacterium tuberculosis (Mtb) igr operon plays an essential role in Mtb cholesterol metabolism, which is critical for pathogenesis during the latent stage of Mtb infection. Here we report the first structure of a heterotetrameric MaoC-like enoyl-CoA hydratase, ChsH1-ChsH2, w...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | ACS Chem Biol |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Chemical
Society
2014
|
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4245171/ https://ncbi.nlm.nih.gov/pubmed/25203216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500232h |
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