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Lifespan extension in C. elegans caused by bacterial colonization of the intestine and subsequent activation of an innate immune response
Mechanisms that control aging are important yet poorly defined. To discover longevity control genes, we performed a forward genetic screen for delayed reproductive aging in C. elegans. Here we show that am117 is a nonsense mutation in the phm-2 gene, which encodes a protein homologous to human scaff...
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| Publicat a: | Dev Cell |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6946027/ https://ncbi.nlm.nih.gov/pubmed/30965033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.03.010 |
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